Single Anastomosis Stomach-Ileal Bypass in Mexico
The Single Anastomosis Stomach-Ileal Bypass with Sleeve Gastrectomy (SASi-S) is a recent advance in metabolic and bariatric surgery that combines two well-established operations: sleeve gastrectomy (VSG) and mini-gastric bypass (MGB). The SASI-S surgical procedure can also be considered a modified version of SADI-S with similar weight reduction and resolution of comorbidities, but a lower risk of complications and malnutrition.
The SASI-S procedure minimizes the risks commonly seen with traditional malabsorptive surgeries. It is specifically designed for both obese and super-obese patients.
Mexico Bariatric Center’s experienced bariatric surgeons begin the procedure by removing about 70% of the stomach to create a sleeve-shaped pouch. The lower portion of the stomach is then connected directly to the ileum, effectively bypassing a section of the small intestine.
This comprehensive guide provides key information for anyone exploring SASi surgery in Mexico.

How SASi-S Works
The main mechanism of action in bariatric surgeries like SASI-S extends beyond simple restriction or malabsorption. This procedure triggers hormonal changes, such as increases in GLP-1 and GIP, to help reduce hunger and improve blood sugar control. Furthermore, elevated bile acid levels and shifts in the gut microbiome contribute to the metabolic improvements seen after SASI-S.


SASi-S Weight Loss Timeline
The SASI Bypass presents a highly effective surgical solution for individuals dealing with obesity and its related health conditions. This procedure not only helps patients lose a significant amount of excess weight but also improves issues like type 2 diabetes, hypertension, and sleep apnea. Most patients see near-complete resolution of their excess weight within the first two years.
Long-term follow-up data demonstrate the efficacy of SASI-S:
- 1 Year: 87% excess weight loss
- 2 Years: 91% excess weight loss
- 3 Years: 81% excess weight loss
These numbers represent average outcomes. Achieving 100% excess weight loss is possible, but individual results may vary.

SASI-S Potential Benefits
SASI yields significant and sustained weight loss with improvement or resolution of comorbidities like type 2 diabetes, high blood pressure, and sleep apnea. Compared to other bypass procedures, RNY gastric bypass, mini gastric bypass, duodenal switch (BPD/DS), and single anastomosis duodenal switch (SADI-S), there is:
SASI-S Risks and Considerations
While SASI-S carries certain risks, they are generally lower compared to other complex bariatric procedures, making it a safer option for many patients.

What Does the SASi-S Package Include?
The cost of Single Anastomosis Stomach-Ileal Bypass can easily surpass $30,000 in the U.S. and Canada, especially without insurance. By choosing Mexico for your weight loss surgery, you can save as much as 70%, while still receiving care that meets or exceeds U.S. standards. Our all-inclusive package starts at $8,495 $6,495* and takes care of every detail from your arrival in San Diego to your departure, including ground transportation and hotel accommodations.
Do I Qualify for SASi-S?
The relatively new SASI-S procedure is designed to take advantage of two effective and common procedures, the gastric sleeve and mini-gastric bypass. The long-term effects are still being studied. Pre- and post-operative care, including dietary changes and lifestyle modifications, is essential for long-term success.
Our general requirements include:
Use our BMI calculator to instantly determine if you’re a candidate for SASI-S in Mexico.
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Duodenal Switch Surgery Before and After Photos




































SASI-S Comparisons
Fewer incisions, lower risk, and better nutrient absorption.
Advanced Single Anastomosis Stomach-Ileal Bypass (SASI-S) in Mexico
SASI vs SADI
SASI-S is a simpler version of SADI-S. The main difference is that SADI-S connects the duodenum to the ileum, whereas SASI-S connects the sleeved stomach to the ileum. SADI involves stapling the duodenum, but in SASI, the duodenum stays intact, posing a lower risk.
The less complex connection in SASI-S is associated with a potentially reduced risk of operational and nutritional complications, such as leak or acid reflux.








